Tuesday, 8 November 2011

Question 2

This question can confuse some students because it conforms to the convention of not saying what the wild-type features look like.  Only mutations are written in the description.  If a feature isn't noted, then you can assume it's wild-type.  Also be careful when determining the order of the genes and whether they're in coupling or not!  It's from a worksheet that is available online.


A homozygous female with mutations for vestigial wings, blue body, and purple eye colour was mated to a wild-type male.  All the triple hets had blue bodies.  The F1 females were testcrossed and eight classes of progeny were classified as follows:
 
Phenotype

Number
 vestigial, blue, purple
 1572
 wild-type
 1553
 blue, purple
 129
 vestigial
 118
 blue
 29
 vestigial, purple
 39
 vestigial, blue
 1
 purple
 4

  1. Define appropriate gene and allele symbols according to standard conventions.
  2. Diagram the arrangement of alleles on the two homologous chromosomes for both parents (P generation) and the F1.
  3. Draw a genetic map based on these data.  Be sure to mathematically correct for double-crossovers.
Try this question before looking at the video solution below:

(you can get a full-screen version by clicking on the YouTube logo at the bottom-right hand side of the video above).

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